Diflucan and oral contraceptives
Typically, tobacco companies market harm-reduction cigarettes as being safer than traditional “full-flavored” brands, leading many smokers to conclude that the use of harm-reduction brands lowers their exposure to toxicants. But a UC Riverside study now shows that smoke from these “light” or “low-yield” harm-reduction cigarettes retains toxicity and that this toxicity can affect prenatal development.
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Two pregnancies and six cases of intermenstrual bleeding have been described in women using oral contraceptives, attributed to the use of Diflucan. This interaction (if such it is) is rare.
Two pregnancies have been reported, despite the use of oral contraceptives, attributed to an interaction with single 150 mg doses of Diflucan. Intermenstrual bleeding has also been described in six other women on oral contraceptives when given a single 150 mg dose of Diflucan. No withdrawal bleeding was reported m one other patient.
In contrast to these reports, a study in 10 women taking combined oral contraceptives found no evidence that a single 50 mg dose of Diflucan or 50 mg Diflucan daily for 10 days had significant effects on the pharmacokmetics of an oral contraceptive (30 g ethmyloestradiol and 150 mg leveonorgestrel). During clinical trials in which single 150 mg doses of Diflucan were used by over 700 women taking oral contraceptives, no evidence of an interaction was seen.
Not understood Unlike ketoconazole, Diflucan appears to have little effect on liver enzyme activity (P450-cytochrome mediated reactions).
Although the contraceptive failures and intermenstrual bleeding cited here have been attributed to the use of Diflucan, this interaction is not clearly established The weight of evidence suggests that contraceptive failure is very unlikely if Diflucan is given, however spotting and breakthrough bleeding are possible signs of diminished contraceptive effectiveness and the ultracauhous might consider advising the additional use of a barrier method of contraception if pregnancy is to be avoided more certainly.
Introduced in the 1960s, oral contraceptives have been used by about 80 percent of women in the United States at some point in their lives. For women without pre-existing risks for heart disease, the early formulations were generally safe, and the newer ones appear to be even safer, but all the risks and benefits are
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Diflucan is one of the drugs that are commonly applied in treating fungus-based infections. The drug is primarily used to treat yeast infection and toe nail fungus. Diflucan functions by preventing the development of fungus so as to arrest the infection. It does this by enhancing the permeability of cellular membranes, which then results in the
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According to the Vatican’s official newspaper, the contraceptive pill is a major cause of male infertility in the West and is also polluting the environment. An article in L’Osservatore Romano claims there is substantial evidence available to show that the environment is being flooded with synthetic female hormones because of widespread use of oral contraceptives
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Family planning is taken very seriously these days and it should be because of the increasing population. The young couple these days are very careful before getting pregnant, they think about everything before conceiving. Developed and developing countries both have taken measured steps to reduce the unwanted pregnancies. Therefore these days the contraceptive are used
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Researchers at Wake Forest University School of Medicine may be one step closer to understanding why past oral contraceptive use dramatically lowers the risk of ovarian and uterine cancers later in life. While studying the effect of post-menopausal dietary soy consumption on estrogen metabolism in cynomolgus monkeys, Latanya M. Scott, Ph.D., discovered that monkeys
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