Many mouth cancers found too late
A new study reveals an association between prenatal exposure to environmental pollutants and elevated body mass index (BMI) during the first three years of life, as reported in the January 2009 issue of the peer-reviewed journal Environmental Health Perspectives (EHP). The study also found associations between exposures to various pollutants and birth weight and length.
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Worldwide, more than 500,000 new cases of cancer of the mouth are diagnosed each year.
The majority of these cancers are found too late, causing many people to die within five years of finding out they have cancer. There exists much information addressing issues related to the patient who has undergone surgery or chemotherapy but little information related to early diagnosis and referral. In a new article in the Journal of Prosthodontics, researchers led by Michael A. Siegel, DDS, MS, FDS, RCSEd, describe the epidemiology of oral cancer and the diagnostic tools currently available to prosthodontists to ensure that their patients are diagnosed at the earliest possible time.
Although the need for prosthodontics was expected to decline with the promotion of preventive measures, it is actually increasing with the aging population. The highest risk of developing oral cancer is in adults over 40 who use both tobacco and alcohol. However, these cancers can develop in anyone, so annual prosthodontist visits are increasingly important.
The majority of oral, head and neck cancer are initially diagnosed in a late stage, which has a five year prognosis of less than 50 percent. If these tumors are found in their earliest stage, the five year prognosis is 95 percent.
All dentists, including prosthodontists, are specifically trained to detect these tumors in an early stage. Only 28 percent of patients reported ever having had an oral cancer examination. Patients who have lost their teeth must be specifically counseled about returning for prescribed, regular recall examinations. They may wrongly think that, as they do not have all or any of their teeth, they do not need to be regularly followed by a prosthodontist.
Recently, several companies have marketed simple tests intended to aid the dentist in the early detection and diagnosis of oral lesions even before they turn into cancer; these tests are painless and relatively inexpensive. Any sore, lump, or bump in the mouth that bleeds, is enlarging, or will not heal should be evaluated at the earliest possible time.
“If prosthodontists, and other dentists, are more vigilant in performing oral cancer screening examinations on all of their patients, the quality of life and survivability from these cancers will be greatly improved, whereby morbidity and mortality will be greatly reduced,” the researchers conclude.
Human calmodulin-like protein (CLP) is found in many cell types including breast, thyroid, prostate, kidney, and skin. The protein can regulate many cell activities and has a highly specific expression. Gaining an understanding about the expression of CLP in oral epithelial cells and its possible downregulation (or lack of production) in cancer may be a
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The American Society for Gastrointestinal Endoscopy (ASGE) heralds the recent news of a decline in U.S. cancer deaths and incidence rates, with colorectal cancer among the top three cancers with significant declines. ASGE, representing the specialists in colorectal cancer screening, is excited by the report showing that colorectal cancer deaths among men and women dropped
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Power3 Medical Products, Inc. said today that two CIP patent applications have been filed for BC-SeraPro Breast Cancer blood test and biomarkers by Dr. Ira Goldknopf, its president and Chief Scientific Officer. The applications for utility patents are entitled “Identities, Specificities, and Use of Twenty Two (22) Differentially Expressed Protein Biomarkers for Blood Based Diagnosis
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As a part of National Cervical Health Awareness Month, Acting Secretary of Health Everette James has reminded women of the importance of cervical cancer prevention and the need for pap tests. “Every January as we begin a new year, we want to remind all Pennsylvanians to do what they can to improve their overall health,”
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An American Cancer Society reports says despite unprecedented progress in reducing incidence and death rates from colorectal cancer, the gap between blacks and whites continues to grow. The latest data show death rates are about 45 percent higher in African American men and women than in whites. The data come from Colorectal Cancer Facts
Full Post: Still wide racial disparities in colorectal cancer rates