Migraines linked to mental disorders



Genetic Immunity, a US/Hungarian clinical-stage company focused on development of nanomedicines for targeted immune amplification, today announced it has treated the first subject in a Phase II clinical study to evaluate DermaVir Patch. DermaVir Patch, the Company’s lead nanomedicine candidate for treatment-na? HIV-infected individuals, is designed to amplify de novo HIV-specific memory T-cell responses

Full Post: Genetic Immunity announces first patient dosed in trial with DermaVir patch for HIV

Migraine headaches can precede the onset of mental disorders, according to a growing body of knowledge that includes a new study in the January-February 2009 issue of General Hospital Psychiatry.

“Together, migraine and mental disorders cause more impairment than alone,” said lead study author Gregory Ratcliffe. “Patients who have one condition should be assessed for the other so they can be treated holistically. Although it is important to know that both are present, treating one will have an effect on the other.”

Ratcliffe is with the department of psychiatry at the University of Manitoba in Canada. He and his colleagues analyzed data on 4,181 participants in the German National Health Interview and Examination Survey. Migraines were diagnosed by a physician and trained interviewers evaluated participants for mental disorders.

Researchers found that 11 percent of participants had migraines. Participants had a variety of disorders: major depression, general anxiety disorder, dysthymia, bipolar disorder, panic attacks, panic disorder, substance abuse disorders, agoraphobia and simple phobia.

The authors considered two theories that might explain the relationship between migraine and mental disorders. The first theory is that a common factor influences both conditions, such as low activity of enzymes that deactivate certain chemical messages sent to the brain. They also considered a causal relationship: This study and others found that anxiety often precedes migraine, which often precedes depression.

Frederick Taylor, M.D., director of the Park Nicollet Headache Clinic in St. Louis Park, Minn., said that migraine co-morbidities - depression, anxiety and other disorders - affect 83 percent of migraineurs and explain 65 percent of their inability to function in life, more than the pain itself.

According to MAGNUM, a national migraine awareness group, 30 million Americans suffer from migraines and another 8 million are genetically susceptible. Those who suffer from the most disabling type of migraine, intractable migraine, can find it a struggle to function in the workplace.

General Hospital Psychiatry is a peer-reviewed research journal published bimonthly by Elsevier Science. For information about the journal, contact Wayne Katon, M.D., at (206) 543-7177.

Ratcliffe GE, et al. The relationship between migraine and mental disorders in a population-based sample. General Hosp Psychiatry , 31(1), 2009.

http://www.hbns.org

Link




Researchers have hypothesized that people with lower IQs may have a higher risk of adult mental disorders, but few studies have looked at the relationship between low childhood IQ and psychiatric disorders later in life. In a new, long-term study covering more than three decades, researchers at Harvard School of Public Health (HSPH) found that

Full Post: People with lower IQs may have greater risk of mental disorders



According to the latest figures from the Agency for Healthcare Research and Quality (AHRQ) in the United States, one in five hospital admissions are for patients with mental disorders. The AHRQ report says in 2006 about 1.4 million hospitalizations involved patients who were admitted for a mental illness, while another 7.1 million patients had a

Full Post: One in five U.S. hospital admissions are for patients with mental disorders



Though effective treatments are available for individuals suffering from chronic depression and anxiety, very little is known about how often these treatments are used or how prevalent these conditions are among the nation’s general population. But in a first-of-its-kind study, UCLA researchers have developed estimates for both the prevalence of chronic psychiatric illness in the

Full Post: 4.7 percent of U.S. population suffers from persistent depression or anxiety disorders



Women who suffer from migraines may take at least some comfort in a recent, first-of-its-kind study that suggests a history of such headaches is associated with a significantly lower risk of breast cancer. Christopher I. Li, M.D., Ph.D., and colleagues at Fred Hutchinson Cancer Research Center report these findings in the November issue of Cancer

Full Post: Migraines linked to lower risk of breast cancer



Earthquakes have aftershocks - not just the geological kind but the mental kind as well. Just like veterans of war, earthquake survivors can experience post-traumatic stress disorder, depression and anxiety. In 1988, a massive earthquake in Armenia killed 17,000 people and destroyed nearly half the town of Gumri. Now, in the first multigenerational study of its

Full Post: Vulnerability to post-traumatic stress runs in families