Introducing presumed consent or opt-out system may increase organ donation rates, suggests a new systematic review published on BMJ.com. There is currently insufficient supply of donor organs to meet the demand for organ transplantations in the UK. The number of patients registered for a transplant continues to increase. In March 2008, 7,655 patients were on
Full Post: Presumed consent or opt-out system may increase organ donation rates
A brand new process that could revolutionise the reliability and durability of surgical implants, such as hip and knee replacements, has today, 2 December 08, received recognition for its medical and commercial potential by achieving one of the world’s most sought after accolades.
A team of researchers, led by the Science and Technology Facilities Council (STFC), has received a Medical Futures Innovation Award for its high technology process designed to coat surgical implants with fibres that, for the first time, will encourage the implant to ‘bond’ with living bone and to last the lifetime of the patient.
This unique surface engineering process is being developed at the Micro-Nano Technology Centre (MNTC) at STFC. In collaboration with the Electrospinning Company Ltd (TECL) and Anglia Ruskin University, the concept will be taken forward under the guidance of a Medical Futures team, and eventually exclusively licensed to TECL, a spin out company of STFC.
This advanced nanotechnology technique builds on an existing technique known as electrospinning, and will utilise a vastly superior electrospinning source to create bespoke fibrous materials. Electrospinning is a process that uses an electrical charge to turn polymers into extremely thin fibres that are ’spun’ to form a mat of fine fibres. It is seen as a platform technology for the medical sector with a wide range of applications including tissue regeneration and drug delivery. The MNTC has developed systems to increase the production rate of nanofibres which has been previously prevented this technology from being adopted by industry.
In this case, nanosized hair- like structures, a thousand times thinner than the width of a human hair, are electrospun at MNTC and added to the surface of an orthopaedic implant to create a ‘living interface’ between the artificial implants and living bone. Not only does this improve the performance of the implants it also significantly increases their durability to last the lifetime of the patient. Any stress on the implant is relieved, making it more reliable and durable. Additionally, it is also possible to add a unique biological coating that can facilitate growth and improve the bonding of healthy tissue to the implant, primarily benefitting patients with osteoarthritis in the aging population and sports injuries in the younger population.
This process will be transferred to UK industry and TECL will provide access to state-of-the-art electrospinning systems. TECL has spun out from STFC to provide open access to electrospinning equipments and expertise to organisations that would like to explore the technique’s potential. The main benefit is that this can be done without commercial companies committing to capital investment or developing in-house expertise until the potential value of electrospinning to the organisation is fully understood. TECL is based both at the Daresbury Science and Innovation Centre in Cheshire and at STFC’s Rutherford Appleton Laboratory in Oxfordshire, and was founded by CLIK, the wholly-owned technology exploitation company of STFC. TECL’s specialised facilities are designed to extend current electrospinning capabilities so that nanofibres can be reproduced in volume.
Dr Robert Stevens, Head of the MNTC at STFC said: “This award provides a major step forward for the future of patients requiring surgical implants and I am thrilled that this concept was selected as an award winner over several hundred entries. Our award is given for translational research innovation to meet the current and future orthopaedic needs of patients.”
Mansel Williams, Chief Executive of The Electrospinning Company said: “Ten percent of patients receiving surgical implants go on to develop infection and loosening of their implants, costing the UK at least £14 million every year, £224 million globally. We want to eliminate this by creating the ideal implant surface matched to the individual patient, benefitting both the patient and the economy. This award will now allow us to scale up the testing and commercialisation of these implants”
The Medical Futures Innovation Awards, which were announced at the Medical Futures Innovators Gallery in London, are one of the UK’s most highly coveted medical awards, rewarding ground-breaking innovation from front line clinicians and scientists with ideas that have the potential to transform peoples’ lives and demonstrate the UK’s position as a world beater.
http://www.stfc.ac.uk
--------------------------------------------------------------------------------------------
Related Posts:
Innocoll, Inc., a privately-held biopharmaceutical company, announced that the FDA has designated Gentamicin surgical implant as a Fast Track development program. Gentamicin surgical implant is currently being evaluated in two phase III clinical trials as an adjunct to systemic antibiotic administration for the prevention of surgical site infections in patients who are at higher
Full Post: Innocoll receives fast track designation for Gentamicin surgical implant
Each year thousands of patients undergo total hip replacement surgery in order to help alleviate pain associated with debilitating hip disease and other related hip problems. According to a new study published in the January 2009 issue of The Journal of Bone and Joint Surgery, while many successful, long-term results have been documented, limited information
Full Post: Total hip replacement surgery
Patients with cochlear implants may want to steer clear of certain magnetic imaging devices, such as 3T MRI machines, because the machines can demagnetize the patient’s implant, according to new research published in the December 2008 issue of Otolaryngology - Head and Neck Surgery. A cochlear implant is an electronic device that restores partial hearing
Full Post: Magnetic imaging devices may damage cochlear implants
Physicians at the University of Illinois Medical Center at Chicago performed a rare surgery this week to restore hearing to a deaf patient. Marisela Leon, 44, has neurofibromatosis type 2 — a rare genetic condition that causes tumors to grow on nerves in the brain or spinal cord, but most commonly on the auditory nerve.
Full Post: Physicians perform rare surgery to restore hearing to a deaf patient
Marinomed Biotechnologie GmbH has been awarded the top prize in the Mercur 2008 innovation awards. This award to Marinomed honours the discovery of antiviral properties in a natural product and the rapid development of the discovery into a nasal spray for treating the common cold. The prestigious prize, presented by the Vienna branch of
Full Post: Natural product from red seaweed brings new antiviral spray --------------------------------------------------------------------------------------------
