Strong relationship between our health as adults and our early diet
Bolder BioTechnology, Inc. today announced that it has been awarded a $1.9 million Phase II Small Business Innovation Research (SBIR) grant from the National Institute of Allergy and Infectious Diseases (NIAID) of The National Institutes of Health (NIH). The grant will be used to perform additional preclinical toxicology and pharmacology studies of the company’s proprietary
Full Post: Bolder BioTechnology awarded NIH grant to continue development of growth hormone product
If you have trouble keeping weight off and you’re wondering why - the surprising answer may well be the cheeseburgers you ate - when you were a toddler.
Surprising new research by University of Calgary, Faculty of Kinesiology researcher Dr. Raylene Reimer, published in an international journal, indicates a direct connection between an adult’s propensity to put on weight and our early childhood diet.
Reimer is a leader in a growing field of study that examines the developmental origins of health and disease. Researchers in this area believe our pre-natal and early childhood environment influences our future risk of developing conditions like cardio vascular disease, obesity and diabetes.
“My research has shown that the food we eat changes how active certain genes in our body are - what we call genetic expression. In particular we believe that our diet has a direct influence on the genes that control how our bodies store and use nutrients,” says Reimer. “There’s a growing body of work that indicates a relationship between our health as adults and our early diet, and even our mother’s diet. This research shows for the first time that our early childhood diet may have a huge impact on our health as adults.”
Reimer’s study published in the current Journal of Physiology (London,) compares three groups of rats. At a very young age the rats were weaned onto three separate diets. One group was fed a high protein diet; one group was fed a high fibre diet and a third group was fed a control diet. When the rats became adults, they were switched to a high fat, high sugar diet, which reflects the reality of the typical western diet.
The results were astonishing. The group of rats who were reared on the high protein diet as packed on much more weight and body fat than the rats who had ‘grown up’ eating the high-fibre diet, who put on the least amount of weight and body fat.
“I believe this study clearly shows that the composition of early childhood diet may have a direct lifelong impact on genes that control metabolism and obesity risk,” says Reimer. “This study clearly indicates that diet composition alone can change the trajectory of circulating satiety hormones and metabolic pathways that influence how we gain weight or control blood sugar as adults.”
A study in rats shows that exposure to a high-fat diet during pregnancy produces permanent changes in the offspring’s brain that lead to overeating and obesity early in life, according to new research by Rockefeller University scientists. This surprising finding, reported in the Nov. 12 issue of the Journal of Neuroscience , provides a key
Full Post: High-fat diet during pregnancy makes new cells in fetal brain that cause early onset obesity
Lining the upper portion of the small intestine with an impermeable sleeve led to both weight loss and restoration of normal glucose metabolism in an animal model of obesity-induced diabetes. Investigators from the Massachusetts General Hospital (MGH) Weight Center and Gastrointestinal Unit report in the journal Obesity that the procedure reproducing several aspects of gastric
Full Post: A potential new procedure for treating obesity
Researchers at Albert Einstein College of Medicine of Yeshiva University have found that overactivity of a brain enzyme may play a role in preventing weight gain and obesity. The findings were reported in Cell Metabolism. To understand what drives hunger and causes metabolic disease, many scientists have focused on the hypothalamus, an almond-sized structure located
Full Post: Overactive brain enzyme may play role in preventing weight gain and obesity
A traditional Mediterranean diet with an additional daily serving of mixed nuts appears to be useful for managing some metabolic abnormalities in older adults at high risk for heart disease, according to a report in the December 8/22 issue of Archives of Internal Medicine. The metabolic syndrome is a set of metabolic abnormalities that includes
Full Post: Nuts and Mediterranean diet appear to help metabolic syndrome
In a six-month comparison of low-carb diets, one that encourages eating carbohydrates with the lowest-possible rating on the glycemic index leads to greater improvement in blood sugar control, according to Duke University Medical Center researchers. Patients who followed the no-glycemic diet experienced more frequent reductions, and in some cases elimination, of their need for medication
Full Post: ‘Low-carb’ best diets for type 2 diabetes