Women risk their lives by failing to take breast cancer drugs
The hormone deprivation therapy that prostate cancer patients often take gives them only a temporary fix, with tumors usually regaining their hold within a couple of years. Now, researchers at Johns Hopkins have discovered critical differences in the hormone receptors on prostate cancer cells in patients who no longer respond to this therapy. The findings,
Full Post: Why prostate cancer patients fail hormone deprivation therapy
Breast cancer patients are risking their lives by failing to take the tamoxifen they are prescribed, according to a new study published in the British Journal of Cancer.
Half of the women failed to finish a five year course of the drug and one in five regularly forget to take a tablet.
Experts already know that taking tamoxifen for five years increases survival chances and the new research reveals that women who miss at least one tablet every five days have a 10 per cent greater risk of dying.
The researchers - based at the University of Dundee and funded by the Medical Research Council and Breast Cancer Research (Scotland) - used the prescription records of more than 2000 women to see how many did not complete the standard treatment of a tamoxifen tablet every day and linked this to other health records to see if they were more likely to die.
The results show that 10 per cent of women followed for one year stopped taking tamoxifen, 19 per cent of the women followed for at least two years had stopped, 32 per cent of the women followed for three and a half years had stopped and a total of 51 per cent of women followed for five or more years had stopped taking the drug.
The study also showed that younger women were more likely to stop taking the medication early but there was no difference in the rich or poorer groups of women.
Professor Alastair Thompson, based at Ninewells Hospital Dundee and the senior breast specialist on the study, said: “This study paints a worrying picture. Tamoxifen is prescribed for five years to offer the best chance of surviving breast cancer, and not taking the tablets means that many women could be disadvantaged. Doctors and nurses should encourage patients to keep taking their prescribed medications, ensure side effects are managed as best as possible and thus get the maximum benefit from the medication.”
Dr Lesley Walker, Cancer Research UK’s director of information, said: “We know that tamoxifen saves lives, so these results are a real concern. It’s not disastrous if women simply forget to take the occasional tablet but if they forget regularly and don’t complete their treatment we need to know why. We need to make it clear that taking tamoxifen regularly for the full five years gives women the best chance of surviving breast cancer. If women are experiencing problems in taking any medication then we urge them to consult their doctor.”
Tamoxifen is an effective drug used for the treatment of certain kinds of breast cancer. The doctors also prescribe the drug for women who are at a higher risk for breast cancer. The drug can be taken in empty stomach and also with food. The drug will have its effect only if it is regularly
Full Post: Tamoxifen is an effective drug used for the treatment of certain kinds of breast cance
The power of the drug tamoxifen to reduce breast density is key in preventing breast cancer - according to a presentation in America by Cancer Research UK scientists. Researchers monitored the extent to which tamoxifen could reduce breast density in 7000 healthy post menopausal women who are at high risk of breast cancer in a
Full Post: How tamoxifen prevents breast cancer in some women but not others
CANCER RESEARCH UK scientists have discovered the molecular basis for tamoxifen response in breast cancer cells - and the reason why some women can develop resistance to the treatment, according to a study published in Nature today (Wednesday). Tamoxifen is given to most women for five years after they are first diagnosed with breast cancer
Full Post: Scientists crack the code to tamoxifen resistance
Women who have a strong family history of breast cancer are over four times more likely to develop the disease than the general population, according to research published in the British Journal of Cancer. This is the first time the risk for women who do not have a faulty BRCA gene but have one first-degree
Full Post: Breast cancer four times more likely in women with strong family history
Problems are everywhere in this world. Majorly these problems are related to the health of the person. Some of the people do regular exercises for their medical fitness because they care about their health. They know about their diet that is why they remain healthy physically and mentally. If a man is mentally and physically
Full Post: Know about Novaldex