Cytori announces seven new investigator-initiated clinical studies in Japan



In treating flare-ups in chronic obstructive pulmonary disease (COPD), a major cause of disability and the fourth leading cause of death in the U.S, what was old is important again. University at Buffalo researchers Sanjay Sethi, M.D., and Timothy F. Murphy, M.D., principal investigators on the longest-running study of infection in COPD patients in

Full Post: Study looks at ‘vicious circle’ theory infections in COPD patients

Cytori has announced it has been informed that seven new investigator-initiated clinical studies in Japan using adipose-derived regenerative cells have been approved by local ethical committees.

The approvals are at leading academic university hospitals and include a diverse group of therapeutic applications.

All seven studies are investigator-initiated and to be performed under local and country guidelines. Cytori, who will not sponsor these studies, will continue work with country authorities, such as the Ministry of Health and Labor in Japan, to obtain specific regulatory approvals for its products. Data from these investigator-initiated studies may benefit Cytori in the future by establishing and broadening the utility for Cytori’s Celution System platform currently sold in more than 30 countries around the world.

“There is a real groundswell of interest within the medical community to explore the full potential of adipose-derived regenerative cells,” said Marc H. Hedrick, M.D., President of Cytori Therapeutics. “In countries where we have regulatory approval today, there may be an emerging market for the sale of Celution Systems for cell processing and for translational research similar to the work being performed in Japan.”

Investigator-initiated studies are sponsored entirely by each hospital, which independently oversees data monitoring and reporting. The breadth of applications being investigated reflects the broad potential for adipose-derived regenerative cells. The indications being investigated in the seven new studies are as follows:

  • Restoration and reconstruction of facial wasting induced by HIV therapy
  • Restoration of speech from vocal cord paralysis
  • Breast reconstruction after cancer treatment without radiation therapy
  • Healing of chronic wounds
  • Chronic liver insufficiency and cirrhosis
  • Urinary incontinence in female patients
  • Peripheral vascular disease

http://www.cytoritx.com

Link




Cytori Therapeutics, Inc. reported preclinical study results, which demonstrate the potential benefit of adipose-derived stem and regenerative cells (ADRCs) for the treatment of damaged intervertebral discs, evidenced by significantly increased disc tissue density and disc-specific extracellular matrix components at 12-months post treatment in a large animal model. The data were presented today at the 2008

Full Post: Cytori reports benefit of adipose-derived regenerative cells in spinal disc model



A study published in the current issue of Cell Transplantation (Vol.17, No. suggests that mature adipocytes - fat cells - could become a source for cell replacement therapy to treat central nervous system disorders. According to the study’s lead researcher, Dr. Yuki Ohta of the Institute of Medical Science, St. Mariana University School of

Full Post: Transplanted fat cells restore function after spinal cord injury



For breast cancer patients who underwent a mastectomy who undergo radiation therapy after immediate breast reconstruction, autologous tissue reconstruction provides fewer long-term complications and better cosmetic results than tissue expander and implant reconstruction, according to a study in the November issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society

Full Post: Type of breast reconstruction procedure impacts radiation therapy outcomes



Tissue Genesis, Inc. has announced that effective immediately, the Tissue Genesis Cell Isolation System will be available to the European marketplace. The Tissue Genesis Cell Isolation System is a fully automated system that recovers potentially regenerative cells from a patient’s own fat in about an hour, with minimal operator intervention. No tissue pre-processing is required.

Full Post: Tissue Genesis applies CE Mark to tissue genesis cell isolation system



Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat more quickly, according to a new study from Karolinska Institutet. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes. The growth of fat cells and their metabolism

Full Post: Control of blood vessels a possible weapon against obesity