Nanoporous ceramic membranes could provide breakthroughs for implantable medical devices
Dyax Corp. has announced that the U.S. Food and Drug Administration (FDA) has accepted for filing the Company’s Biologics License Application (BLA) for DX-88 (ecallantide) for the treatment of acute attacks of hereditary angioedema (HAE) and has designated the application for Priority Review. Based on this designation, the FDA Prescription Drug User Fee Act (PDUFA)
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A team of researchers led by North Carolina State University has made a breakthrough that could lead to new dialysis devices and a host of other revolutionary medical implants.
The researchers have found that the unique properties of a new material can be used to create new devices that can be implanted into the human body - including blood glucose sensors for diabetics and artificial hemo-dialysis membranes that can scrub impurities from the blood.
Researchers have long sought to develop medical devices that could be implanted into patients for a variety of purposes, such as monitoring glucose levels in diabetic patients. However, existing materials present significant problems. For example, devices need to be made of a material that prevents the body’s proteins from building up on sensors and preventing them from working properly. And any implanted device also needs to avoid provoking an inflammatory response from the body that would result in the body’s walling off the device or rejecting it completely.
Now a new study finds that nanoporous ceramic membranes may be used to resolve these issues. Dr. Roger Narayan - an associate professor in the joint biomedical engineering department of NC State and the University of North Carolina at Chapel Hill - led the research and says the nanoporous membranes could be used to “create an interface between human tissues and medical devices that is free of protein buildup.”
The new research, published in a special issue of Biomedical Materials , is the first in-depth study of the biological and physical properties of the membranes. The study suggests that the human body will not reject the nanoporous ceramic membrane. Narayan adds that this could be a major advance for the development of kidney dialysis membranes and other medical devices whose development has been stalled by poor compatibility with human tissues. Narayan was also the lead researcher on the team that first developed these new materials.
Solianis has just finalised a test series in which patients with diabetes have worn the first configuration of the multisensor system for non-invasive Continuous Glucose Monitoring at home and at work. Results show that the system tracks glucose in these settings and that it is sensitive to hyper- and hypoglycemic glucose excursions. “This is the
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Surplus energy generated by the heart may one day help power pacemakers and defibrillators implanted in cardiac patients, according to research presented at the American Heart Association’s Scientific Sessions 2008. In a trailblazing experiment, a microgenerator powered by heartbeats produced almost 17 percent of the electricity needed to run an artificial pacemaker. “This was a
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Using an array of nanotube devices, each coated with a different organic material, researchers at the Israel Institute of Technology have developed diagnostic system that may be able to diagnose lung cancer simply by sampling a patient’s breath. The results of this study, which was led by Hossam Haick, Ph.D., appear in the journal Nano
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Patients with cochlear implants may want to steer clear of certain magnetic imaging devices, such as 3T MRI machines, because the machines can demagnetize the patient’s implant, according to new research published in the December 2008 issue of Otolaryngology - Head and Neck Surgery. A cochlear implant is an electronic device that restores partial hearing
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Headphones for MP3 players placed within an inch of pacemakers and implantable cardioverter defibrillators (ICDs) may interfere with these devices, according to research presented at the American Heart Association’s Scientific Sessions 2008. Researchers investigated the effects of MP3 player headphones, most of which contain the magnetic substance neodymium, on the operation of implanted cardiac devices
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