Pre-existing diabetes for persons diagnosed with cancer associated with increased risk of death
When asked by health care professionals about their health, older African-American adults consistently report poorer health than whites of the same age do - even if both groups are functioning extremely well, a new study finds. “Asking how a person would rate his or her health remains one of the simplest tools that a health
Full Post: Racial differences in self-rated health at similar levels of physical functioning
Patients with diabetes at the time of a cancer diagnosis have an increased risk of death compared to patients without diabetes, according to a meta-analysis of studies reported in the December 17 issue of JAMA, the Journal of the American Medical Association.
Approximately 20 million Americans have diabetes mellitus, which is about 7 percent of the U.S. adult population. Diabetes mellitus appears to be a risk factor for some cancers, but the effect of pre-existing diabetes on all-cause death in newly diagnosed cancer patients is less clear, according to background information in the article.
Bethany B. Barone, Sc.M., of the Johns Hopkins Bloomberg School of Public Health, Baltimore, and colleagues conducted a meta-analysis to examine the association of pre-existing diabetes with long-term, all-cause death in cancer patients. The researchers identified 48 articles that met criteria for the study, including 23 articles for which data could be included in the meta-analysis.
The meta-analysis (of these 23 studies) indicated that pre-existing diabetes was associated with an increase in all-cause death following cancer diagnosis, compared with individuals with normal glucose levels, across all cancer types. Additional analyses by type of cancer showed that pre-existing diabetes was significantly associated with increased long-term, all-cause death for cancers of the endometrium, breast, and colorectum. Diabetes was associated with a nonsignificant increase in risk in prostate, gastric, hepatocellular, lung and pancreatic cancer.
“Future research should determine the relative importance of different pathways to diabetes-related mortality risk. If a clinical or biological interaction between diabetes and cancer care is confirmed, subsequent trials should test whether improvements in diabetes care for patients with newly diagnosed cancer might reduce long-term mortality,” the authors conclude.
The risk of non-AIDS cancer is higher for individuals infected with HIV than for the general population, according to a meta-analysis presented here at the American Association for Cancer Research’s Seventh Annual International Conference on Frontiers in Cancer Prevention Research. Compared with the general population, the risk for non-AIDS cancers was 2.3 times higher for
Full Post: Risk of non-AIDS cancer higher for individuals infected with HIV
An analysis of previous studies indicates that smoking is significantly associated with an increased risk for colorectal cancer and death, according to an article in the December 17 issue of JAMA, the Journal of the American Medical Association. Although tobacco was responsible for approximately 5.4 million deaths in 2005, there are still an estimated 1.3
Full Post: Smoking significantly linked to increased risk for colorectal cancer
Patients with type 2 diabetes who have poor glycemic control and a certain genetic variation have an increased risk of coronary artery disease, according to a study in the November 26 issue of JAMA, the Journal of the American Medical Association. Among the known risk factors for cardiovascular disease, diabetes mellitus ranks as one of
Full Post: Genetic variation for persons with diabetes linked to greater risk of coronary artery disease
Coincident with the widespread adoption of PSA screening, the proportion of American men diagnosed with organ-confined, low risk prostate cancer has increased significantly during the last two decades. In a study scheduled for publication in the February 2009 issue of The Journal of Urology, researchers report that for low-income men, the opposite is true, with
Full Post: Low income men diagnosed more often with advanced prostate cancer
An American Cancer Society reports says despite unprecedented progress in reducing incidence and death rates from colorectal cancer, the gap between blacks and whites continues to grow. The latest data show death rates are about 45 percent higher in African American men and women than in whites. The data come from Colorectal Cancer Facts
Full Post: Still wide racial disparities in colorectal cancer rates