Study evaluates corneal collagen cross-linking in subjects with progressive keratoconus
New research shows that the cost of health insurance for a typical family increases about $100 per month when state governments limit price adjustments based on factors like age, health or risky behaviors such as smoking. The finding by Brigham Young University economist Mark Showalter is one of several examples of how one state’s set
Full Post: Cost of health insurance rises 33% with state pricing rule
Presently keratoconus is treated through eyeglasses, hard contact lenses, and a newer treatment, INTACS plastic rings inserted into the mid layer of the cornea to flatten it, changing the shape and location of the cone.
In 15-20% of the cases, cornea transplant surgery is necessary. The Cornea Research Foundation of America is one of 9 sites in the U.S. currently participating in a new clinical research investigation to study the benefits of corneal collagen cross-linking (CXL) in subjects with progressive keratoconus and corneal ectasia after prior refractive surgery. These studies are the first in the U.S. of CXL designed to assess the safety and effectiveness of CXL for slowing the progression of both of these conditions.
“Because the FDA usually requires data from two separate studies before approving a new drug or device, we are conducting two cross-linking studies: one is for the treatment of keratoconus and the other is for treatment of post-refractive ectasia, a rare complication of refractive surgery,” says Marianne Price, executive director of the Cornea Research Foundation of America.
The FDA permitted study is sponsored by Swiss-based Peschke Meditrade GmbH. Corneal collagen cross-linking is a procedure that involves administering riboflavin and UVA in carefully selected parameters that strengthen the front layers of the cornea and avoid damage to the back of the eye. The riboflavin and UVA light source that is used for CXL are both investigational in the United States and are not yet approved by the FDA.
The Foundation started the collagen cross-linking study in January 2008. The FDA has given permission for enrollment of 160 patients into each study. People interested in more information about the study or participating in the study can contact the Cornea Research Foundation of America. Subjects may be eligible for the study if they have the following in one or both eyes, or are:
- 18 years of age or older
- Have been diagnosed with progressive keratoconus or have had previous vision correction surgery and now have corneal ectasia
- Vision with contact lenses or glasses is worse than 20/20
- Corneal thickness greater than 300 microns at the thinnest point
- If you are female, you cannot be pregnant
- Can leave contact lenses out for at least 3 months in the eye to be treated
- If you have keratoconus, you cannot have had previous corneal surgery or Intacs
- If you have keratoconus, it must have gotten worse in the last two years based on your previous eye exams. You will need to contact your eye doctor or allow us to contact your eye doctor to get your eye exam records for your vision measurements, corneal maps (topography) and contact lens or glasses prescriptions.
Expert Source: Dr. Marianne Price, executive director of the Cornea Research Foundation of America. Dr. Price is a sought after speaker and published author, a member of the American Academy of Ophthalmology, the Association for Research in Vision and Ophthalmology, the American Society of Cataract & Refractive Surgery, and Ophthalmic Women Leaders. Dr. Price holds a bachelor’s degree in engineering science from the University of Notre Dame and both an MBA in finance and a doctorate in medical and molecular genetics from Indiana University.
The 2008 Joint Meeting of the American Academy of Ophthalmology (Academy) and European Society of Ophthalmology (SOE), the largest and most comprehensive ophthalmic educational meeting in the world, is in session November 8 to 11 at the Georgia World Congress Center, Atlanta. Offerings include 277 continuing medical education courses, 179 ” Breakfast with the Experts
Full Post: Advances in ophthalmology
Find yourself squinting to identify someone across the room or getting headaches from staring at your computer screen for too long? If so, you may need glasses or contact lenses. Since January is National Eye Care Month, Garden City, New York-based Sterling Optical has compiled the following list of signs to consider before you head
Full Post: Do I need glasses?
The U.S. Food and Drug Administration announced a Class I recall of lot no. UD30654 of Healon D, an ophthalmic viscosurgical device (OVD) manufactured by Advanced Medical Optics Inc. (AMO) of Santa Ana, Calif. OVDs are viscoelastic materials used to maintain space in the eye during surgery. Typically, OVDs are pre-packaged in a syringe and
Full Post: FDA announces recall of ophthalmic viscosurgical device
Abbott and Advanced Medical Optics (AMO) have announced a definitive agreement for Abbott to acquire AMO for $22 per share in cash, for a total transaction value of approximately $2.8 billion, inclusive of estimated net debt at the time of closing. Based in Santa Ana, Calif., AMO is a global leader in ophthalmic care, comprised
Full Post: Abbott to acquire Advanced Medical Optics
Household budget cutbacks are becoming commonplace as most Americans struggle to make ends meet, but experts warn that health care needs should not be among the forfeited services. Recent research indicates that more than 20 percent of people have cut back on medical visits to save money and The Vision Council warns that this cost-saving
Full Post: Household budget cutbacks in health care could have serious consequences