Warning about Vicks VapoRub
XTL Biopharmaceuticals Ltd. has announced the top-line results from the Bicifadine Phase 2b clinical trial for the treatment of diabetic neuropathic pain. The trial’s primary objective was to compare the efficacy of two doses of Bicifadine against placebo in reducing pain associated with diabetic neuropathy. The primary endpoint of the study was the reduction in
Full Post: XTL Biopharmaceuticals announces results from Bicifadine in diabetic neuropathic pain trial
A warning has been issued about the popular cough and cold treatment Vicks VapoRub. Experts say it should not be used on children under 2 years of age.
Vicks VapoRub, a salve which can be bought over the counter, is used to relieve coughs and congestion, but can apparently harm infants and toddlers.
According to Dr. Bruce Rubin from Wake Forest University School of Medicine, Vicks VapoRub can have severe effects on breathing in young children because it may stimulate mucus production and airway inflammation.
The product made by Procter and Gamble has been around since 1905 - it is applied to the chest or throat for congestion relief or to relieve sore muscles.
It contains camphor which is toxic if swallowed or absorbed into the body and the manufacturers do in fact warn that VapoRub should not be applied in or near the nostrils and not used on children under 2 years of age.
Dr. Rubin was first alerted to the dangers of the misuse of the Vaporub when an 18-month-old child developed severe respiratory distress after it was put directly under her nose.
Dr. Rubin says the ingredients in Vicks can be irritants, causing the body to produce more mucus to protect the airway and infants and young children have airways that are much narrower than those of adults, so any increase in mucus or inflammation can narrow them more severely.
Research was then carried out on the effects of the salve on the respiratory system of animals - ferrets, which have an airway system similar to humans, were used and tests conducted which measured the effects of the Vaporub on mucus secretion and build up in the airways, and fluid build up in the lungs.
It was found that the Vaporub increased the mucus secretion and decreased the clearance of the mucus and Dr. Rubin says Vicks should not be put in or under, the nose of adults or children and never used in children under age 2.
He says even when the directions on the label are followed Vicks may make people with congestion feel more comfortable, but it does nothing to increase airflow or actually relieve the congestion and he suggests similar products, including generic brands, could cause the same adverse reaction in infants and toddlers.
The Wake Forest team say cough and cold medicines and decongestants are dangerous and neither effective nor safe for young children and medications which dry up nasal passages also present problems.
Dr. Rubin says the best treatments for congestion are saline (salt water) and gentle rubber bulb suction, warm drinks or chicken soup, and, often, just letting time heal the child.
However Dr. Rubin says a child struggling to breathe is a medical emergency and needs would to be seen by a doctor as quickly as possible.
Experts recommend parents check with a doctor before giving infants and young children any over-the-counter medicine as they can be harmful.
Proctor & Gamble says Vicks VapoRub has a long-standing history of being safe and effective when used according to package directions and it’s safety and efficacy has been demonstrated in multiple human clinical trials including more than a thousand children aged 1 month to 12 years.
The company says the findings of the animal studies, prompted by a single case report, are of questionable human clinical relevance.
The research is published the current issue of CHEST.
New research out of Wake Forest University Baptist Medical Center suggests that Vicks VapoRub, the popular menthol compound used to relieve symptoms of cough and congestion, may instead create respiratory distress in infants and small children. The study appears in this month’s issue of Chest , the peer-reviewed journal of the American College of Chest
Full Post: Vicks VapoRub may create respiratory distress in young children
A booster vaccination for parents of new babies and other household members may be the most effective way of preventing the fatal form of whooping cough in young infants, say a group of paediatric intensive care doctors on bmj.com. Whooping cough (pertussis) is a distressing infectious disease which affects infants and young children. Vaccination is
Full Post: Parents of new babies should be considered for a whooping cough booster, say experts
After a doctor at Adelaide’s Women’s and Children’s Hospital tested positive for tuberculosis (TB), authorities say as many as 300 babies have been identified who may have come into contact with the doctor and could be at risk. About 75 of the children are too young to be tested but have been given preventive
Full Post: As many as 300 children could be at risk of TB from hospital doctor
A virus that causes cold-like symptoms in humans originated in birds and may have crossed the species barrier around 200 years ago, according to an article published in the December issue of the Journal of General Virology. Scientists hope their findings will help us understand how potentially deadly viruses emerge in humans. “Human metapneumovirus may
Full Post: Common cold virus originated in birds
A Kansas State University graduate student has found a correlation between childhood obesity and asthma. Sara Rosenkranz, doctoral student in human nutrition, Manhattan, conducted research that found that healthy children with higher levels of body fat and lower levels of physical activity had greater amounts of airway narrowing after exercise. “Kids who are overweight and
Full Post: Link between childhood obesity and asthma